Chemo Neurolysis

Also known as “chemical neurolysis,” chemo neurolysis is a pain management procedure that uses special chemical agents to precisely target and intentionally damage or destroy peripheral nerves in order to relieve pain. The damaged nerves are no longer able to send pain signals to the brain.

Chemo neurolysis is most often used for patients experiencing severe or chronic pain that have not responded to other treatments, such as medications or physical therapy. It is commonly used to treat neuropathic pain, cancer pain and visceral pain (pain from internal organs). It may be used to treat Morton’s Neuroma, a type of inflammation and pain experienced in the feet. In some cases, it is used to treat spasticity, a neurological condition that can affect movement and speech.

Performed by an interventional radiologist who uses imaging to guide the procedure, chemo neurolysis involves the application of a chemical agent (ethanol, phenol or glycerol) injected close to the nerve sensing the pain. The chemical agent destroys the nerve, effectively blocking its pain signals. This results in less pain, as well as improvements in range of motion and mobility.

Chemo neurolysis is meant to provide longer term pain relief, and the treatment can last for several months or years. Every patient’s experience is different. It is performed on an outpatient basis. After the procedure, patients are observed to ensure they are not experiencing any side effects, and then permitted to return home.

Possible risks of chemo neurolysis include nerve damage, pain, weakness, sensory disturbances, infection and in extremely rare cases, prolonged paralysis.

For more information about chemo neurolysis, or to schedule a consultation with one of our doctors, please visit our contact page or call (720) 516-0637.